Since the 1990s, creatine supplementation has been hailed as a shortcut to improving or recovering from physical demands on our body. Most studies concentrated on improvements with athletic performance or recovery. Creatine is formed in our bodies from three amino acids, methionine, arginine, and glycine, all of which can be found in any animal protein source that we consume. Creatine is made from these three amino acids in the liver, but also to a lesser extent the kidneys and pancreas also make creatine and store it in the form of phosphocreatine. It is the phosphocreatine compound donating the P to convert ADP to ATP, the primary energy carrier within the mitochondria that is showing many more health benefits than previously imagined with creatine supplementation.