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Monday, June 20 2022

Mitochondrial Health Part 4 – Supplemental Support

We have already discussed some important methods and supplements but since it is such a complex subject, in this newsletter I will try and give reasons why these additional supplements should be considered as important activators for improving mitochondrial health by increasing ATP and energy within our cells. These supplements have multiple benefits beyond helping the mitochondria, but for the sake of this newsletter I will keep it specific to mitochondrial health benefits.

 

D-Ribose

This is a sugar found within beef, eggs, and dairy. Aging, and exercise can reduce ATP, and D-Ribose will bring back energy from lowered ATP. Taken by capsule or powder in ranges from 3-5 grams is recommended. From what I have read on it, taking it for one month to see if it is helping. There was a study in 2015 from Ohio State that showed an improvement in congestive heart failure in 64% of the subjects when supplementation of D-Ribose was administered over six weeks. Cautions: Some people report gastrointestinal symptoms and lowered blood sugar when taking it, so anyone with hypoglycemia or even those who are on insulin need to be cautious.

 

Resveratrol

This is an antioxidant found in the seeds, and skins of grapes and berries. This study in 2017 showed improvement in mitochondrial respiratory dysfunction. There does not appear to be any cautions to be concerned about with resveratrol.

 

L-Carnitine

An amino acid that transports long-chain fatty acids into your mitochondria ...  (keep reading)

Posted by: Dr.Goldstein AT 08:26 am   |  Permalink   |  0 Comments  |  Email
Friday, May 20 2022

 

In the world of anti-aging research, there has been a large focus on N.A.D. which is
a natural compound in all cells of our body. It is a critical molecule in that it helps

cells unlock energy from food and create ATP, a process that occurs in the mitochondria. It is also a signaling molecule to tell cells it needs repair and maintenance. N.A.D. is high when we are young, and declines throughout life by a factor of 50% every 20 years. If you could keep your N.A.D. levels elevated, you could theoretically pause or even reverse signs and symptoms of aging.

 

N.A.D. stands for nicotinamide adenine dinucleotide. It will be much easier to refer to it as NAD. Made from vitamin B3 (nicotinic acid or nicotinamide/niacinamide) and to a lesser extent from tryptophan. NAD exists as NAD+, NADH, NADP+, and NADPH. NAD is a redox couple where the NAD+ and NADP+ are the oxidized forms and NADH and NADPH are in the reduced form. When oxidized, it loses electrons and when reduced it is gaining electrons and NAD in these coenzyme forms are responsible for all metabolic transformations that take place within our bodies. Without them we would die within 30 seconds. This is how cyanide works. Cyanide shuts down the cytochrome c oxidase enzyme in the mitochondria which is the last step in the process of making ATP and oxygen. Cyanide makes oxygen unavailable.

Posted by: Dr. Goldstein AT 06:42 pm   |  Permalink   |  0 Comments  |  Email
Sunday, April 24 2022

Last month’s article was devoted to the importance of mitochondrial health in the production of energy for the body in the form of ATP. This currency of energy used by the body is important not only in movement of muscles, but also the movement of energy for clear thinking, the movement to activate immune system responses, and the energy for reducing pain. To summarize, it all happens with food we consume through the Krebs Cycle and combining NADH with oxygen as it passes through the Electron Transport Chain to form water and carbon dioxide. This happens in the 250 quadrillion mitochondria we have within all our cells. However, there is a missing piece to this process, which is the importance of red and infrared light on our mitochondria.  Keep Reading>>

Posted by: Dr. Goldstein AT 12:33 pm   |  Permalink   |  0 Comments  |  Email
Tuesday, March 22 2022

The Importance of Mitochondrial Health

Mitochondria are organelles that apart from red blood cells, exist in mind boggling numbers throughout our bodies.  Mitochondria, which are responsible for providing energy for the body, vary in number according to the different types of cells in the body. The largest concentration of mitochondria is in our brain, neurons, and heart where there could be thousands of mitochondria in each cell providing energy needed for cognition and movement. It is estimated that we have 250 quadrillion mitochondria in us and that mitochondria make up about 20% of our body weight.  Additionally, our immune system depends on mitochondrial health to have the energy to defeat infections that arise from time to time. Persistent infections are a likely sign that the immune system lacks the energy to recover even when healing procedures are administered. There is abundant evidence that damaged or diminished mitochondrial functionality is a key reason for the onset of almost every degenerative disease we commonly hear about along with an accelerated or normal decline in aging.

Posted by: Dr. Goldstein AT 12:56 pm   |  Permalink   |  0 Comments  |  Email
Tuesday, February 22 2022

The Uric Acid Marker

Dr. Richard Johnson has spent the past twenty years researching why we get fat so easily, and how fructose and uric acid play an important role in contributing to most of the major health problems we see today including heart disease, obesity, high blood pressure, dementia, and Alzheimer’s disease.  In his third book titled Why Nature Wants Us to Be Fat, Johnson uses his unique background in Anthropology, as a kidney specialist, and research background to detail how human physiology and diet have influenced the epidemic of the most common health problems seen today.

 

If you were to play a word association game with any physician and said uric acid the response would probably be Gout in nearly 100% of the cases. Uric acid is a waste product from the breakdown of the nucleic acids DNA and RNA of the purines that are elevated in red meat, sardines, shrimp, and brewer’s yeast.  If those purines crystalize in a joint such as the big toe, this is Gout, and it can be very painful.

 

What Dr. Johnson has discovered is that uric acid is also a downstream byproduct of the metabolism of fructose, and this is the key to what Dr. Johnson talked about in his second book called The Fat Switch...

Posted by: Dr. Goldstein AT 08:03 am   |  Permalink   |  0 Comments  |  Email
 

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